A new diabetes drug is helping overweight people lose a quarter of their body weight. In recent research, about nine out of 10 persons with obesity lose weight. The United States Food and Drug Administration recently approved this drug to treat people with type 2 diabetes. But it can also help adults without diabetes lose weight as well. Scientists study the drug called Tirzepatide in people without diabetes in dosages of 5, 10 and 15 milligrams.
Weekly doses of tirzepatide were tested in more than 2500 persons without diabetes. Persons in the research also received counseling sessions to help them stay on a healthy diet. Participants with obesity or who were overweight and took the 5-milligram injection dose lost an average of 16 kilograms. Participants on the 10-milligram injection dose lost an average of 22 kilograms. Those on the 15-milligram injection dose lost an average of 23.6 kilograms.
Almost 40% of participants lost a quarter of their body weight. People who got a placebo (A placebo is an inert substance or treatment that has no therapeutic effect on a person's health condition, but is given to the patient with the belief that it will improve their condition) lost between 2.4% and 3.1% of their body weight.
This shocking range of weight loss was possible only through surgery. Scientists said that obesity should be treated like any other chronic problem using approaches that target underlying disease mechanisms. The recent results show that tirzepatide may be doing just that.
Currently, tirzepatide is not FDA-approved as an overweight medication for the treatment of obesity. In May 2022, Tirzepatide was FDA-approved for the treatment of type 2 diabetes. Obesity or overweight is defined as excessive or abnormal fat accumulation that may negatively affect your health. Obesity or overweight has nearly tripled since 1975 according to the World Health Organization.
Around 2 billion adults, 18 years and older were overweight in 2016. Of those, over 650 million were obese, 39% of adults aged 18 years and over were overweight in 2016 and 13% were obese. 39 million children under the age of 5 were obese or overweight in 2020. After reading this article following questions may arise in your mind.
How Does Tirzepatide Work For Weight Loss?
(2) Does tirzepatide have side effects?
(3) Is tirzepatide available now for weight loss?
(4) Is tirzepatide safe for the kidneys?
(5) Is tiezepatide a pill or an injection?
(6) What is the other name for tirzepatide?
(7) Is tirzepatide being prescribed?
(8) Can people without diabetes take tirzepatide?
(9) Will tirzepatide be approved for weight loss?
(10) Is tirzepatide better than semaglutide for weight loss?
(1) How expensive is tirzepatide?
The cost of tirzepatide can vary depending on various factors. Factors such as the country, the pharmacy, the dose, the duration of treatment, and the patient's insurance coverage. In the United States, as of 2021, the wholesale acquisition cost (WAC) of tirzepatide is approximately $845 per pen for the 5 mg/1.5 mL strength. And $1690 per pen for the 10 mg/1.5 mL strength.
However, it is important to note that the actual cost may differ based on insurance coverage and discounts provided by pharmacies or drug manufacturers. Patients are encouraged to consult with their healthcare provider and their insurance company or pharmacist to determine the most accurate and up-to-date cost information for tirzepatide in their specific location.
(2) Does tirzepatide have side effects?
Yes, tirzepatide can cause side effects, like any medication. Common side effects of tirzepatide include Gastrointestinal symptoms such as nausea, vomiting, diarrhea, constipation, and abdominal pain. Decreased appetite, Headache, Dizziness and Fatigue. Injection site reactions such as redness, itching, or pain. Hypoglycemia (low blood sugar) when used in combination with insulin or other medications that lower blood sugar levels.
Less common but more serious side effects of tirzepatide may include pancreatitis (inflammation of the pancreas), kidney problems, or allergic reactions. If you experience any unusual symptoms while taking tirzepatide. It is important to contact your healthcare provider right away. Your healthcare provider will be able to help you manage any side effects and determine if the medication is appropriate for you.
(3) Is tirzepatide available now for weight loss?
Tirzepatide is a medication currently under development by Eli Lilly and Company for the treatment of obesity and type 2 diabetes. According to sources, tirzepatide had not yet been approved by the US Food and Drug Administration (FDA) or other regulatory agencies for the treatment of obesity. However, clinical trials have shown promising results for weight loss with tirzepatide, and it may become available for this use in the future. It is important to consult with a healthcare provider for the most up-to-date information on medications for weight loss.
(4) Is tirzepatide safe for the kidneys?
Tirzepatide is a medication that is currently being investigated for the treatment of type 2 diabetes and obesity. As with any medication, tirzepatide has potential side effects, including effects on the kidneys.
Clinical trials have shown that tirzepatide can cause a slight decrease in the estimated glomerular filtration rate (eGFR). eGFR is a measure of kidney function. However, in these trials, the decrease in eGFR was generally mild and reversible. There were no cases of acute kidney injury or other serious kidney problems associated with tirzepatide use.
It is important to note that individuals with kidney disease or a history of kidney problems should be closely monitored if they are considering taking tirzepatide or any other medication for diabetes or obesity. Before starting any new medication, it is important to discuss your medical history and any potential risks with your healthcare provider.
(5) Is tiezepatide a pill or an injection?
Tirzepatide is administered by injection, not as a pill. It is a once-weekly injection that is typically self-administered under the skin (subcutaneously) using a pre-filled pen device. The injection is intended for use in the treatment of type 2 diabetes.
The pre-filled pen device contains a fixed dose of tirzepatide, and it is important to follow the instructions for use carefully to ensure the correct dose is administered. Tirzepatide injections should only be used under the guidance of a healthcare professional, who can provide instructions on proper injection technique and dosing.
(6) What is the other name for tirzepatide?
Tirzepatide is the generic name for the medication, but it is also known by its brand name, which is Mounjaro. Mounjaro (tirzepatide) is a medication that is used for the treatment of type 2 diabetes and obesity. It belongs to a class of medications called glucagon-like peptide-1 (GLP-1) receptor agonists, which work by increasing insulin secretion and suppressing glucagon secretion in response to meals. tirzepatide is typically administered as a once-weekly injection under the skin.
(7) Is tirzepatide being prescribed?
Tirzepatide is not yet approved for prescription and commercial use in all countries. As of September 2021, tirzepatide was in the advanced stages of clinical development and had shown promising results in clinical trials for the treatment of type 2 diabetes and obesity.
Once tirzepatide is approved for prescription and commercial use. it will likely be prescribed by healthcare professionals to eligible patients who have been diagnosed with type 2 diabetes or obesity. However, it is important to note that tirzepatide may not be appropriate for everyone, and it should only be used under the guidance and supervision of a healthcare professional.
(8) Can people without diabetes take tirzepatide?
Tirzepatide is a medication that has been developed primarily for the treatment of type 2 diabetes. As of September 2021, tirzepatide had not yet been approved for any other uses.
While tirzepatide may have potential benefits for weight loss in people without diabetes. It is important to note that the medication has not yet been studied extensively in this population. Additionally, tirzepatide can cause side effects, and its safety and effectiveness in people without diabetes has not been fully established.
If you are considering using tirzepatide for weight loss or any other purpose. It is important to discuss your individual circumstances and medical history with a healthcare professional to determine whether the medication is appropriate for you. Only a healthcare professional can prescribe tirzepatide and provide guidance on its use.
(9) Will tirzepatide be approved for weight loss?
Tirzepatide is a medication that is currently has been developed for the treatment of type 2 diabetes. Clinical trials have shown promising results for weight loss with tirzepatide. And the medication is being studied specifically for this use.
As of my September 2021, tirzepatide had not yet been approved by the US Food and Drug Administration (FDA) or other regulatory agencies for the treatment of obesity. However, if further studies continue to show positive results for weight loss. It is possible that tirzepatide may be approved for this use in the future.
It is important to note that even if tirzepatide is approved for weight loss. It should only be used under the guidance of a healthcare professional and in combination with a healthy diet and regular physical activity. Additionally, tirzepatide is not suitable for everyone, and its use may be associated with certain side effects.
(10) Is tirzepatide better than semaglutide for weight loss?
Tirzepatide and semaglutide are both GLP-1 receptor agonists that have been studied for weight loss in clinical trials.
The results of clinical trials suggest that tirzepatide may be more effective than semaglutide for weight loss. In a Phase 2 clinical trial, patients receiving tirzepatide lost an average of 13.7% of their body weight compared to an average of 2.3% for patients receiving semaglutide. In a Phase 3 clinical trial, patients receiving tirzepatide lost an average of 12.4% of their body weight compared to an average of 6.2% for patients receiving semaglutide.
However, it is important to note that both tirzepatide and semaglutide are effective weight loss treatments and may have different side effect profiles and dosing requirements. Treatment decisions should be made in consultation with a healthcare professional.
CONCLUSION
Overall, tirzepatide shows promising potential as a treatment for weight loss and type 2 diabetes. However, further research is needed to fully understand its safety, efficacy, and long-term effects. It is important for individuals to discuss the potential benefits and risks of tirzepatide with a healthcare professional before considering its use.
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